| Stage | 2 |
| Price | 200 |
| Type | Explosive |
| Damage per second | 310 |
| Abbreviations | nade |
| Name for Binds | gren (Item), grenade (Weapon) |
| Clip Size | 1 |
| Clip Count | 1 |
| Splash Damage | 192 |
The Grenade, activated through the inventory, is a simple weapon to use, but is also a very powerful tool for the Humans. A Human can only carry one. The throw of a grenade cannot be increased by a great deal, and its range is short, thus making Tremulous's grenade not as useful in on-the-run encounters as the grenades of other First-Person Shooters. However, damage dealt at the epicenter of the grenade explosion is in excess of a massive 340 points, easily more than enough to kill anything other than a Tyrant. It is a great advantage for the humans against poorly-constructed Alien defenses: the grenade can obliterate a large group of Acid Tubes, provided that they are clustered tightly together. A common tactic is to enter the Alien base suicidially with nothing but Light Armor, a Painsaw, and a grenade, attack the Overmind and/or an egg farm, and release the grenade at the last second, thereby ensuring the destruction of the target. This is known as a painsaw rush.